Browsing by Author "Rothhammer Engel, Francisco"

Now showing items 1-20 of 22

    • Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based ... 
      Ruiz Linares, Andrés; Adhikari, Kaustubh; Acuña Alonzo, Víctor; Quinto Sánchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; de Avila, Francisco; Gómez Valdés, Jorge; León Mimila, Paola; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Burley, Mari-Wyn; Konca, Esra; Zagonel de Oliveira, Marcelo; Veronez, Mauricio Roberto; Rubio Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolás; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Schuler Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria-Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Balding, David; González José, Rolando (Public Library of Science, 2014)
      The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social ...
    • Alcoholism and heredity. A critical update Alcoholismo y herencia. Una actualizacion critica. 
      Rothhammer Engel, Francisco; Moreno Moreno, Claudia; Llop Romero, Elena (1994)
      The etiology of alcoholism is under constant revision. This work critically examines the accumulated evidence on the degree of genetic determination of alcoholism, aiming to provide an updated view of the problem. The ...
    • ApoE alleles and tau markers in patients with different levels of cognitive impairment 
      Lavados Montes, Manuel; Farías, Gustavo; Rothhammer Engel, Francisco; Guillón Moretti, Marta; Mujica, María; Maccioni, Cristóbal; Maccioni Baraona, Ricardo (ELSEVIER SCIENCE INC, 2005-09)
      Background. The presence of brain hyperphosphorylated tau constitutes a hallmark of neurodegenerative disorders of the Alzheimer's type. This report describes the relationships between tau markers in the cerebrospinal fluid ...
    • Danko Brncic y la coadaptación 
      Rothhammer Engel, Francisco; Manríquez Soto, Germán Raúl (Sociedad de Biología de Chile, 2001)
      El concepto de coadaptación es antiguo en biología. Darwin (1859) se refiere a la "gran cantidad de complejas e indispensables coadaptaciones estructurales existentes entre un ser orgánico y otro". El concepto también fue ...
    • Distribution of alleles of DRD4 and DAT1 genes of the dopaminergic system in the mixed Chilean population ... 
      Vieyra S, Gonzalo; Moraga V, Mauricio; Henríquez B, Hugo; Aboitiz Domínguez, Francisco Javier; Rothhammer Engel, Francisco (2003)
      Background: Genes for dopamine receptor DRD4 and dopamine transporter DAT1 are highly polymorphic. Two alleles of these genes, namely the DRD4.7 and the DAT1*9 are frequently associated to the attention deficit disorder ...
    • Estimadores de mezcla amerindia basados en métodos serológicos y moleculares 
      Pulgar Alarcón, Iván; Fuentes Guajardo, Macarena; Llop Romero, Elena; Rothhammer Engel, Francisco (Soc Médica Santiago, 2015)
      Background: Amerindian admixture is an important parameter to consider in epidemiological studies in American countries, to make a proper selection of cases and controls. Aim: To compare Amerindian admixture estimates ...
    • Genetic composition of the Chilean population: the population from San Pedro de Atacama Composicion genética ... 
      Acuña Acuña, Jeannette; Llop Romero, Elena; Rothhammer Engel, Francisco (1994)
      This work describes the genetic composition of atacameños from San Pedro de Atacama. The results show that a) the contribution of non-indigenous genes is relatively low, in relation to the spanish immigration period. b) ...
    • Genetic composition of the Chilean population: the Yamanas from Ukika Composición genética de la población ... 
      Llop Romero, Elena; Harb,; Moreno Moreno, Claudia; Aspillaga, Angela; van de Maele,; Rothhammer Engel, Francisco (1994)
      The genetic composition of a group of 24 Yamana indians that survive in Puerto Williams, Navarino Island, Chile (parallel 55 south of Tierra del Fuego), was studied. Results showed that these indians have a different genetic ...
    • Genetic susceptibility to Andes Hantavirus: Association between severity of disease and HLA alleles in ... 
      Ferrer C., Pablo; Vial C., Pablo A.; Ferrés, Marcela; Godoy M., Paula; Cuiza V., Analia; Marco C., Claudia; Castillo H., Constanza; Umaña C., María Elena; Rothhammer Engel, Francisco; Llop Romero, Elena (2007)
      Andes hantavirus (ANDV) infection in Chile has a variable clinical expression, and infected individuals may present with different grades of disease severity. This study aimed to determine if clinical expression of ANDV ...
    • A genome-wide association study identifies multiple loci for variation in human ear morphology 
      Adhikari, Kaustubh; Reales, Guillermo; Smith, Andrew J.P.; Konka, Esra; Palmen, Jutta; Quinto Sánchez, Mirsha; Acuña Alonzo, Víctor; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Barquera Lozano, Rodrigo; Macín Pérez, Gastón; Gómez Valdés, Jorge; Villamil Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Calderón, Rosario; Rosique, Javier; Cheeseman, Michael; Bhutta, Mahmood F.; Humphries, Steve E.; González José, Rolando; Headon, Denis; Balding, David; Ruiz Linares, Andrés (Nature Publishing, 2015)
      Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, ...
    • Genotypic interaction between DRD4 and DAT1 loci is a high risk factor for attention-deficit/hyperactivity ... 
      Carrasco Álvarez, Ximena; Rothhammer Achondo, Paula; Moraga Vergara, Mauricio; Henríquez B., Hugo; Chakraborty, Ranajit; Aboitiz Domínguez, Francisco Javier; Rothhammer Engel, Francisco (WILEY-LISS, 2006-01-05)
      Attention-deficit/hyperactivity disorder, ADHD [MIM 126452], is a common, highly heritable neurobiological disorder of childhood onset, characterized by hyperactivity, impulsiveness, and/or inattentiveness. As part of an ...
    • Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos 
      Fuentes, Macarena; Pulgar, Iván; Gallo, Carla; Bortolini, María; Canizales Quinteros, Samuel; Bedoya, Gabriel; González José, Rolando; Ruiz Linares, Andrés; Rothhammer Engel, Francisco (Sociedad Médica de Santiago, 2014)
      Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
    • HLA Antigens in cardiomyopathic Chilean chagasics 
      Llop Romero, Elena; Rothhammer Engel, Francisco; Acuna,; Apt Baruch, Werner (1988)
      The distribution of HLA antigens in a sample of 124 Chagas serologically positive Chilean individuals was studied. The sample was subdivided according to the presence or absence of chagasic cardiomyopathy, in order to ...
    • Implications of the admixture process in skin color molecular assessment 
      Silva de Cerqueira, Caio Cesar; Hünemeier, Tábita; Gómez Valdés, Jorge; Ramallo, Virginia; Volasko Krause, Carla Daiana; Leal Barbosa, Ana Angélica; Vargas Pinilla, Pedro; Ciconet Dornelles, Rodrigo; Longo, Danaé; Rothhammer Engel, Francisco; Bedoya, Gabriel; Canizales Quinteros, Samuel; Acuña Alonzo, Víctor; Gallo, Carla; Poletti, Giovanni; González José, Rolando; Mauro Salzano, Francisco; Callegari-Jacques, Sídia María; Schuler-Faccini, Lavínia; Ruiz Linares, Andrés; Bortolini, María Cátira (PLOS One, 2014)
      The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ...
    • Major histocompatibility system as a risk factor for alcoholic liver disease El sistema mayor de ... 
      Llop Romero, Elena; Hirsch Birn, Sandra; Maza Cave, María Pía de la; Bunout Barnett, Daniel; Iturriaga,; Silva Silva, Laura; Ugarte,; Rothhammer Engel, Francisco (1995)
      Several associations between alleles of the major histocompatibility system and alcoholic liver disease have been described. However, these are weak and change from one population to another. The aim of this work was to ...
    • Microdiferenciación genética de una población indígena de habla aymara en la provincia de Arica, Chile 
      Rothhammer Engel, Francisco (Universidad de Chile., 1977)
      Las frecuencias genéticas de catorce sistemas enzimáticos eritricitarios (fosfohxosa isomerasa, fosfatasa acida, adenilato kinasa, adenosin deaminasa, 6 fosfogluconato deshidrogenasa, isocitrato deshidrogenasa, malato ...
    • Morphometric and mtdna analyses of archaic skeletal remains from southwestern south america 
      Manríquez Soto, Germán Raúl; Moraga Vergara, Mauricio; Santoro, Calogero; Aspillaga Fontaine, Eugenio; Arriaza, Bernardo T.; Rothhammer Engel, Francisco (2011)
      For decades anthropologists have discussed how and when the Americas were peopled. The prevailing view is that the first Paleoindians, ancestors of the Amerindians, arrived from Asia and Beringia to the American continent ...
    • Paleodemography in mummies of prehispanic populations from Africa Paleodemografía en momias de poblaciones ... 
      Moreno Moreno, Claudia; Rothhammer Engel, Francisco; Aspillaga, Angela (1992)
      Mummies' demographic information of 10 prehispanic cultures that developed in the Arica region of Chile about 7000 years ago is analyzed and related to the present population structure. A paleoepidemiological analysis ...
    • Patterns of Y-chromosome variation in South Amerindians [1] 
      Rothhammer Engel, Francisco; Moraga,; Tarazona-Santos,; Carvalho-Silva,; Pettener,; Luiselli,; De Stefano,; Martinez-Labarga,; Rickards,; Tyler-Smith,; Pena,; Santos, (University of Chicago Press, 2001)
    • Perinatal variables from newborns of Aymara mothers suggest a genetic adaptation to high altitude Variables ... 
      Pizarro Ortiz, María; Barra, Rodrigo; Gajardo, Felipe; Fuentes Guajardo, Macarena; Rothhammer Engel, Francisco (Sociedad Médica de Santiago, 2014)
      Background: Studies performed in Andean populations living in high altitude, indicate that the reduced availability of oxygen could be associated to both a fetal growth retardation and a lower birth weight. These variables ...